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Revealing the Effects of Missense Mutations Causing Snyder-Robinson Syndrome on the Stability and Dimerization of Spermine Synthase

Missense mutations in spermine synthase (SpmSyn) protein have been shown to cause the Snyder-Robinson syndrome (SRS). Depending on the location within the structure of SpmSyn and type of amino acid substitution, different mechanisms resulting in SRS were proposed. Here we focus on naturally occurrin...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Peng, Yunhui, Norris, Joy, Schwartz, Charles, Alexov, Emil
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730321/
https://ncbi.nlm.nih.gov/pubmed/26761001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17010077
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