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Selenocysteine tRNA([Ser]Sec), the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification and Sequencing

The selenocysteine (Sec) tRNA([Ser]Sec) population consists of two isoforms that differ from each other by a single 2’-O-methylribosyl moiety at position 34 (Um34). These two isoforms, which are encoded in a single gene, Trsp, and modified post-transcriptionally, are involved individually in the syn...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Carlson, Bradley A., Lee, Byeong Jae, Tsuji, Petra A., Copeland, Paul R., Schweizer, Ulrich, Gladyshev, Vadim N., Hatfield, Dolph L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836751/
https://ncbi.nlm.nih.gov/pubmed/28917036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7258-6_4
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