The utilization of selenocysteine-tRNA([Ser]Sec) isoforms is regulated in part at the level of translation in vitro

The tRNA for the 21st proteinogenic amino acid, selenocysteine, exists in mammalian cells as 2 isoforms differing by a single 2′-O-methylribosyl moiety at position 34 (Um34). These isoforms contain either 5-methoxycarbonylmethyluridine (mcm(5)U) or 5-methoxycarbonylmethyl-2′-O-methyluridine (mcm(5)U...

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Publicado en:Translation (Austin)
Autores principales: Carlson, Bradley A., Gupta, Nirupama, Pinkerton, Mark H., Hatfield, Dolph L., Copeland, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Short Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501377/
https://ncbi.nlm.nih.gov/pubmed/28702279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21690731.2017.1314240
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