Selective Removal of the Selenocysteine tRNA([Ser]Sec) Gene (Trsp) in Mouse Mammary Epithelium

Mice homozygous for an allele encoding the selenocysteine (Sec) tRNA([Ser]Sec) gene (Trsp) flanked by loxP sites were generated. Cre recombinase-dependent removal of Trsp in these mice was lethal to embryos. To investigate the role of Trsp in mouse mammary epithelium, we deleted this gene by using t...

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Autori principali: Kumaraswamy, Easwari, Carlson, Bradley A., Morgan, Fanta, Miyoshi, Keiko, Robinson, Gertraud W., Su, Dan, Wang, Shulin, Southon, Eileen, Tessarollo, Lino, Lee, Byeong Jae, Gladyshev, Vadim N., Hennighausen, Lothar, Hatfield, Dolph L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC151713/
https://ncbi.nlm.nih.gov/pubmed/12588969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1477-1488.2003
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