Selective Removal of the Selenocysteine tRNA([Ser]Sec) Gene (Trsp) in Mouse Mammary Epithelium

Mice homozygous for an allele encoding the selenocysteine (Sec) tRNA([Ser]Sec) gene (Trsp) flanked by loxP sites were generated. Cre recombinase-dependent removal of Trsp in these mice was lethal to embryos. To investigate the role of Trsp in mouse mammary epithelium, we deleted this gene by using t...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Kumaraswamy, Easwari, Carlson, Bradley A., Morgan, Fanta, Miyoshi, Keiko, Robinson, Gertraud W., Su, Dan, Wang, Shulin, Southon, Eileen, Tessarollo, Lino, Lee, Byeong Jae, Gladyshev, Vadim N., Hennighausen, Lothar, Hatfield, Dolph L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151713/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1477-1488.2003
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