Inhibition of selenocysteine tRNA([Ser]Sec) aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA

There are two isoforms of selenocysteine (Sec) tRNA([Ser]Sec) that differ by a single methyl group, Um34. The non-Um34 isoform supports the synthesis of a subclass of selenoproteins, designated housekeeping, while the Um34 isoform supports the expression of another subclass, designated stress-relate...

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Bibliographic Details
Main Authors: Kim, Jin Young, Carlson, Bradley A., Xu, Xue-Ming, Zeng, Yu, Chen, Shawn, Gladyshev, Vadim N., Lee, Byeong Jae, Hatfield, Dolph L.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124823/
https://ncbi.nlm.nih.gov/pubmed/21624347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.05.096
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