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High expression of class III β-tubulin has no impact on functional cancer cell growth inhibition of a series of key vinblastine analogs

Clinical association studies have implicated high expression of class III β-tubulin as a predictive factor for lower response rates and reduced overall survival in patients receiving tubulin binding drugs, most notably the taxanes. Because of the implications, we examined a series of key vinblastine...

詳細記述

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書誌詳細
出版年:Bioorg Med Chem Lett
主要な著者: Radakovic, Aleksandar, Boger, Dale L.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835219/
https://ncbi.nlm.nih.gov/pubmed/29439899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.02.006
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