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High expression of class III β-tubulin has no impact on functional cancer cell growth inhibition of a series of key vinblastine analogs
Clinical association studies have implicated high expression of class III β-tubulin as a predictive factor for lower response rates and reduced overall survival in patients receiving tubulin binding drugs, most notably the taxanes. Because of the implications, we examined a series of key vinblastine...
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| Veröffentlicht in: | Bioorg Med Chem Lett |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835219/ https://ncbi.nlm.nih.gov/pubmed/29439899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.02.006 |
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