An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors

The adoptive transfer of neoantigen-reactive tumor-infiltrating lymphocytes (TILs) can result in tumor regression in patients with metastatic cancer. To improve the efficacy of adoptive T cell therapy targeting these tumor-specific mutations, we have proposed a new therapeutic strategy, which involv...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Lu, Yong-Chen, Zheng, Zhili, Robbins, Paul F., Tran, Eric, Prickett, Todd D., Gartner, Jared J., Li, Yong F., Ray, Satyajit, Franco, Zulmarie, Bliskovsky, Valery, Fitzgerald, Peter C., Rosenberg, Steven A.
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835023/
https://ncbi.nlm.nih.gov/pubmed/29174843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.10.018
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