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An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors
The adoptive transfer of neoantigen-reactive tumor-infiltrating lymphocytes (TILs) can result in tumor regression in patients with metastatic cancer. To improve the efficacy of adoptive T cell therapy targeting these tumor-specific mutations, we have proposed a new therapeutic strategy, which involv...
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| Izdano u: | Mol Ther |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Gene & Cell Therapy
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835023/ https://ncbi.nlm.nih.gov/pubmed/29174843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.10.018 |
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