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Regulatory mechanisms of hypoxia‐inducible factor 1 activity: Two decades of knowledge

Hypoxia‐inducible factor 1 (HIF‐1) is a transcriptional activator of various genes related to cellular adaptive responses to hypoxia. Dysfunctions in the regulatory systems of HIF‐1 activity have been implicated in the pathogenesis of various diseases including malignant tumors and, thus, elucidatin...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Koyasu, Sho, Kobayashi, Minoru, Goto, Yoko, Hiraoka, Masahiro, Harada, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834787/
https://ncbi.nlm.nih.gov/pubmed/29285833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13483
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