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Regulatory mechanisms of hypoxia‐inducible factor 1 activity: Two decades of knowledge

Hypoxia‐inducible factor 1 (HIF‐1) is a transcriptional activator of various genes related to cellular adaptive responses to hypoxia. Dysfunctions in the regulatory systems of HIF‐1 activity have been implicated in the pathogenesis of various diseases including malignant tumors and, thus, elucidatin...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Koyasu, Sho, Kobayashi, Minoru, Goto, Yoko, Hiraoka, Masahiro, Harada, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834787/
https://ncbi.nlm.nih.gov/pubmed/29285833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13483
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