NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease

Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD). Nlrx1(−/−) mice have exacerbated disease severity, colonic lesions, and increased inflammatory markers. Global transcriptomic analyses demonst...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Leber, Andrew, Hontecillas, Raquel, Tubau-Juni, Nuria, Zoccoli-Rodriguez, Victoria, Abedi, Vida, Bassaganya-Riera, Josep
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834749/
https://ncbi.nlm.nih.gov/pubmed/29535731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00363
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