NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease

Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD). Nlrx1(−/−) mice have exacerbated disease severity, colonic lesions, and increased inflammatory markers. Global transcriptomic analyses demonst...

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Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Leber, Andrew, Hontecillas, Raquel, Tubau-Juni, Nuria, Zoccoli-Rodriguez, Victoria, Abedi, Vida, Bassaganya-Riera, Josep
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834749/
https://ncbi.nlm.nih.gov/pubmed/29535731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00363
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