NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease

Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD). Nlrx1(−/−) mice have exacerbated disease severity, colonic lesions, and increased inflammatory markers. Global transcriptomic analyses demonst...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Leber, Andrew, Hontecillas, Raquel, Tubau-Juni, Nuria, Zoccoli-Rodriguez, Victoria, Abedi, Vida, Bassaganya-Riera, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834749/
https://ncbi.nlm.nih.gov/pubmed/29535731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00363
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