Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor

Derivation of human hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) offers considerable promise for cell therapy, disease modeling, and drug screening. However, efficient derivation of functional iPSC-derived HSCs with in vivo engraftability and multilineage potential rem...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Tan, Yu-Ting, Ye, Lin, Xie, Fei, Beyer, Ashley I., Muench, Marcus O., Wang, Jiaming, Chen, Zhu, Liu, Han, Chen, Sai-Juan, Kan, Yuet Wai
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834708/
https://ncbi.nlm.nih.gov/pubmed/29386396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718446115
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