Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor

Derivation of human hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) offers considerable promise for cell therapy, disease modeling, and drug screening. However, efficient derivation of functional iPSC-derived HSCs with in vivo engraftability and multilineage potential rem...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tan, Yu-Ting, Ye, Lin, Xie, Fei, Beyer, Ashley I., Muench, Marcus O., Wang, Jiaming, Chen, Zhu, Liu, Han, Chen, Sai-Juan, Kan, Yuet Wai
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834708/
https://ncbi.nlm.nih.gov/pubmed/29386396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718446115
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