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Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column

The N-glycan moiety of IgG-Fc has a significant impact on multifaceted properties of antibodies such as in their effector function, structure, and stability. Numerous studies have been devoted to understanding its biological effect since the exact composition of the Fc N-glycan modulates the magnitu...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kiyoshi, Masato, Caaveiro, Jose M. M., Tada, Minoru, Tamura, Hiroko, Tanaka, Toru, Terao, Yosuke, Morante, Koldo, Harazono, Akira, Hashii, Noritaka, Shibata, Hiroko, Kuroda, Daisuke, Nagatoishi, Satoru, Oe, Seigo, Ide, Teruhiko, Tsumoto, Kouhei, Ishii-Watabe, Akiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834517/
https://ncbi.nlm.nih.gov/pubmed/29500371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22199-8
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