Structural insight and stability of TNFR-Fc fusion protein (Etanercept) produced by using transgenic silkworms

由 Kiyoshi, Masato, Tatematsu, Ken-Ichiro, Tada, Minoru, Sezutsu, Hideki, Shibata, Hiroko, Ishii-Watabe, Akiko
發表在 J Biochem (2020)

Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations

由 Yoshida, Kouhei, Kuroda, Daisuke, Kiyoshi, Masato, Nakakido, Makoto, Nagatoishi, Satoru, Soga, Shinji, Shirai, Hiroki, Tsumoto, Kouhei
發表在 Sci Rep (2019)

Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody

由 Akiba, Hiroki, Tamura, Hiroko, Kiyoshi, Masato, Yanaka, Saeko, Sugase, Kenji, Caaveiro, Jose M. M., Tsumoto, Kouhei
發表在 Sci Rep (2019)

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

由 Kiyoshi, Masato, Caaveiro, Jose M.M., Kawai, Takeaki, Tashiro, Shinya, Ide, Teruhiko, Asaoka, Yoshiharu, Hatayama, Kouta, Tsumoto, Kouhei
發表在 Nat Commun (2015)

Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies

由 Aoyama, Michihiko, Hashii, Noritaka, Tsukimura, Wataru, Osumi, Kenji, Harazono, Akira, Tada, Minoru, Kiyoshi, Masato, Matsuda, Akio, Ishii-Watabe, Akiko
發表在 MAbs (2019)

Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand

由 Kosuge, Hirofumi, Nagatoishi, Satoru, Kiyoshi, Masato, Ishii‐Watabe, Akiko, Tanaka, Toru, Terao, Yosuke, Oe, Seigo, Ide, Teruhiko, Tsumoto, Kouhei
發表在 Biotechnol Prog (2020)

Affinity Improvement of a Therapeutic Antibody by Structure-Based Computational Design: Generation of Electrostatic Interactions in the Transition State Stabilizes the Antibody-Ant...

由 Kiyoshi, Masato, Caaveiro, Jose M. M., Miura, Eri, Nagatoishi, Satoru, Nakakido, Makoto, Soga, Shinji, Shirai, Hiroki, Kawabata, Shigeki, Tsumoto, Kouhei
出版 2014

Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column

由 Kiyoshi, Masato, Caaveiro, Jose M. M., Tada, Minoru, Tamura, Hiroko, Tanaka, Toru, Terao, Yosuke, Morante, Koldo, Harazono, Akira, Hashii, Noritaka, Shibata, Hiroko, Kuroda, Daisuke, Nagatoishi, Satoru, Oe, Seigo, Ide, Teruhiko, Tsumoto, Kouhei, Ishii-Watabe, Akiko
發表在 Sci Rep (2018)