Nanoparticle-Mediated Trapping of Wnt Family Member 5A in Tumor Microenvironments Enhances Immunotherapy for B-Raf Proto-Oncogene-Mutant Melanoma

Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. Approximately 50% of human melanoma is driven by B-Raf proto-oncogene mutation (BRAF-mutant). Tumors with such mutation are desmoplastic, highly immunosuppressive, and often resistant to...

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Udgivet i:ACS Nano
Main Authors: Liu, Qi, Zhu, Hongda, Tiruthani, Karthik, Shen, Limei, Chen, Fengqian, Gao, Keliang, Zhang, Xueqiong, Hou, Lin, Wang, Degeng, Liu, Rihe, Huang, Leaf
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834397/
https://ncbi.nlm.nih.gov/pubmed/29370526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b07384
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