Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.

The genomic and cDNA fragments of Drosophila melanogaster, homologous to human c-raf-1, were cloned. The nucleotide sequence predicted the primary structure of a polypeptide of 666 amino acid residues with a highly conserved Ser-Thr kinase domain on its carboxy terminal half. Draf-1 was mapped to th...

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Bibliographic Details
Main Authors: Nishida, Y, Hata, M, Ayaki, T, Ryo, H, Yamagata, M, Shimizu, K, Nishizuka, Y
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC454391/
https://ncbi.nlm.nih.gov/pubmed/3135183
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