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Nanoparticle-Mediated Trapping of Wnt Family Member 5A in Tumor Microenvironments Enhances Immunotherapy for B-Raf Proto-Oncogene-Mutant Melanoma
Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. Approximately 50% of human melanoma is driven by B-Raf proto-oncogene mutation (BRAF-mutant). Tumors with such mutation are desmoplastic, highly immunosuppressive, and often resistant to...
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| 出版年: | ACS Nano |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834397/ https://ncbi.nlm.nih.gov/pubmed/29370526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b07384 |
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