Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells

Neoantigens are the main targets of tumor-specific T cells reactivated by immune checkpoint-blocking antibodies or when using tumor-infiltrating T cells for adoptive therapy. While cancers often accumulate hundreds of mutations and harbor several immunogenic neoantigens, the repertoire of mutation-s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kato, Taigo, Matsuda, Tatsuo, Ikeda, Yuji, Park, Jae-Hyun, Leisegang, Matthias, Yoshimura, Sachiko, Hikichi, Tetsuro, Harada, Makiko, Zewde, Makda, Sato, Sho, Hasegawa, Kosei, Kiyotani, Kazuma, Nakamura, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834292/
https://ncbi.nlm.nih.gov/pubmed/29541393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24232
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