Neoantigens elicit T cell responses in breast cancer

Neoantigens are tumour-specific antigens that arise from non-synonymous mutations in tumour cells. However, their effect on immune responses in the tumour microenvironment remains unclear in breast cancer. We performed whole exome and RNA sequencing of 31 fresh breast cancer tissues and neoantigen p...

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Pubblicato in:Sci Rep
Autori principali: Morisaki, Takafumi, Kubo, Makoto, Umebayashi, Masayo, Yew, Poh Yin, Yoshimura, Sachiko, Park, Jae-Hyun, Kiyotani, Kazuma, Kai, Masaya, Yamada, Mai, Oda, Yoshinao, Nakamura, Yusuke, Morisaki, Takashi, Nakamura, Masafumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245657/
https://ncbi.nlm.nih.gov/pubmed/34193879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91358-1
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