Neoantigens elicit T cell responses in breast cancer

Neoantigens are tumour-specific antigens that arise from non-synonymous mutations in tumour cells. However, their effect on immune responses in the tumour microenvironment remains unclear in breast cancer. We performed whole exome and RNA sequencing of 31 fresh breast cancer tissues and neoantigen p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morisaki, Takafumi, Kubo, Makoto, Umebayashi, Masayo, Yew, Poh Yin, Yoshimura, Sachiko, Park, Jae-Hyun, Kiyotani, Kazuma, Kai, Masaya, Yamada, Mai, Oda, Yoshinao, Nakamura, Yusuke, Morisaki, Takashi, Nakamura, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245657/
https://ncbi.nlm.nih.gov/pubmed/34193879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91358-1
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