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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

OBJECTIVE: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance of MELK expression in ovarian cancer using clinical samples, and assessed the efficacy of a small...

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Bibliografski detalji
Izdano u:J Gynecol Oncol
Glavni autori: Ikeda, Yuji, Sato, Sho, Yabuno, Akira, Shintani, Daisuke, Ogasawara, Aiko, Miwa, Maiko, Zewde, Makda, Miyamoto, Takashi, Fujiwara, Keiichi, Nakamura, Yusuke, Hasegawa, Kosei
Format: Artigo
Jezik:Inglês
Izdano: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593222/
https://ncbi.nlm.nih.gov/pubmed/33078598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2020.31.e93
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