High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

OBJECTIVE: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance of MELK expression in ovarian cancer using clinical samples, and assessed the efficacy of a small...

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Detalhes bibliográficos
Publicado no:J Gynecol Oncol
Main Authors: Ikeda, Yuji, Sato, Sho, Yabuno, Akira, Shintani, Daisuke, Ogasawara, Aiko, Miwa, Maiko, Zewde, Makda, Miyamoto, Takashi, Fujiwara, Keiichi, Nakamura, Yusuke, Hasegawa, Kosei
Formato: Artigo
Idioma:Inglês
Publicado em: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593222/
https://ncbi.nlm.nih.gov/pubmed/33078598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2020.31.e93
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