Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma

Adoptive cell therapy using TCR-engineered T cells (TCR-T cells) represents a promising strategy for treating relapsed and metastatic cancers. We previously established methods to identify neoantigen-specific TCRs based on patients’ PBMCs. However, in clinical practice isolation of PBMCs from advanc...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Wei, Teng, Leisegang, Matthias, Xia, Ming, Kiyotani, Kazuma, Li, Ning, Zeng, Chenquan, Deng, Chunyan, Jiang, Jinxing, Harada, Makiko, Agrawal, Nishant, Li, Liangping, Qi, Hui, Nakamura, Yusuke, Ren, Lili
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2021
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158031/
https://ncbi.nlm.nih.gov/pubmed/34104546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1929726
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