Genomic BCR-ABL1 breakpoint characterization by a multi-strategy approach for “personalized monitoring” of residual disease in chronic myeloid leukemia patients

For monitoring minimal residual disease (MRD) in chronic myeloid leukemia (CML) the most recommended method is quantitative RT-PCR (RT-qPCR) for measuring BCR-ABL1 transcripts. Several studies reported that a DNA-based assay enhances the sensitivity of detection of the BCR-ABL1 genomic rearrangement...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Cumbo, Cosimo, Impera, Luciana, Minervini, Crescenzio Francesco, Orsini, Paola, Anelli, Luisa, Zagaria, Antonella, Coccaro, Nicoletta, Tota, Giuseppina, Minervini, Angela, Casieri, Paola, Brunetti, Claudia, Rossi, Antonella Russo, Parciante, Elisa, Specchia, Giorgina, Albano, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834283/
https://ncbi.nlm.nih.gov/pubmed/29541390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23971
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