Genomic BCR-ABL1 breakpoint characterization by a multi-strategy approach for “personalized monitoring” of residual disease in chronic myeloid leukemia patients

For monitoring minimal residual disease (MRD) in chronic myeloid leukemia (CML) the most recommended method is quantitative RT-PCR (RT-qPCR) for measuring BCR-ABL1 transcripts. Several studies reported that a DNA-based assay enhances the sensitivity of detection of the BCR-ABL1 genomic rearrangement...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Cumbo, Cosimo, Impera, Luciana, Minervini, Crescenzio Francesco, Orsini, Paola, Anelli, Luisa, Zagaria, Antonella, Coccaro, Nicoletta, Tota, Giuseppina, Minervini, Angela, Casieri, Paola, Brunetti, Claudia, Rossi, Antonella Russo, Parciante, Elisa, Specchia, Giorgina, Albano, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834283/
https://ncbi.nlm.nih.gov/pubmed/29541390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23971
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