TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing

BACKGROUND: The assessment of TP53 mutational status is becoming a routine clinical practice for chronic lymphocytic leukemia patients (CLL). A broad spectrum of molecular techniques has been employed so far, including both direct Sanger sequencing and next generation sequencing. Oxford Nanopore Tec...

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Bibliografiske detaljer
Udgivet i:Diagn Pathol
Main Authors: Minervini, Crescenzio Francesco, Cumbo, Cosimo, Orsini, Paola, Brunetti, Claudia, Anelli, Luisa, Zagaria, Antonella, Minervini, Angela, Casieri, Paola, Coccaro, Nicoletta, Tota, Giuseppina, Impera, Luciana, Giordano, Annamaria, Specchia, Giorgina, Albano, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057401/
https://ncbi.nlm.nih.gov/pubmed/27724982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0550-y
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