High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients

BACKGROUND: Exosomes arise from viable cancer cells and may reflect a different biology than circulating cell-free DNA (cfDNA) shed from dying tissues. We compare exosome-derived DNA (exoDNA) to cfDNA in liquid biopsies of patients with pancreatic ductal adenocarcinoma (PDAC). PATIENTS AND METHODS:...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Ann Oncol
Autori principali: Allenson, K., Castillo, J., San Lucas, F. A., Scelo, G., Kim, D. U., Bernard, V., Davis, G., Kumar, T., Katz, M., Overman, M. J., Foretova, L., Fabianova, E., Holcatova, I., Janout, V., Meric-Bernstam, F., Gascoyne, P., Wistuba, I., Varadhachary, G., Brennan, P., Hanash, S., Li, D., Maitra, A., Alvarez, H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Original articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834026/
https://ncbi.nlm.nih.gov/pubmed/28104621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi