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High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients
BACKGROUND: Exosomes arise from viable cancer cells and may reflect a different biology than circulating cell-free DNA (cfDNA) shed from dying tissues. We compare exosome-derived DNA (exoDNA) to cfDNA in liquid biopsies of patients with pancreatic ductal adenocarcinoma (PDAC). PATIENTS AND METHODS:...
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| Publicado no: | Ann Oncol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834026/ https://ncbi.nlm.nih.gov/pubmed/28104621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx004 |
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