Circulating tumour-derived KRAS mutations in pancreatic cancer cases are predominantly carried by very short fragments of cell-free DNA

BACKGROUND: The DNA released into the bloodstream by malignant tumours· called circulating tumour DNA (ctDNA), is often a small fraction of total cell-free DNA shed predominantly by hematopoietic cells and is therefore challenging to detect. Understanding the biological properties of ctDNA is key to...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zvereva, Maria, Roberti, Gabriel, Durand, Geoffroy, Voegele, Catherine, Nguyen, Minh Dao, Delhomme, Tiffany M., Chopard, Priscilia, Fabianova, Eleonora, Adamcakova, Zora, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Brennan, Paul, Foll, Matthieu, Byrnes, Graham B., McKay, James D., Scelo, Ghislaine, Le Calvez-Kelm, Florence
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251242/
https://ncbi.nlm.nih.gov/pubmed/32249202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.042
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