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Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis
Disrupted Wnt signaling in osteoblastic-lineage cells leads to bone formation defect in osteoporosis. However, the factors repressing Wnt signaling are unclear. In our study, we found that Wnt signaling was suppressed persistently in bone marrow-derived mesenchymal stem cells (BMSCs) during osteopor...
Shranjeno v:
| izdano v: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833865/ https://ncbi.nlm.nih.gov/pubmed/29416009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0231-0 |
| Oznake: |
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