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TIMP-1 inhibits proliferation and osteogenic differentiation of hBMSCs through Wnt/β-catenin signaling

The present study aimed to evaluate the effect of tissue inhibitor of metalloproteinase-1 (TIMP-1) on the proliferation and osteogenic differentiation potential of human bone marrow-derived MSCs (hBMSCs). hBMSCs with stable TIMP-1 overexpression or TIMP-1 knockdown were generated. Osteogenic differe...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Liang, Tangzhao, Gao, Wenling, Zhu, Lei, Ren, Jianhua, Yao, Hui, Wang, Kun, Shi, Dehai
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328886/
https://ncbi.nlm.nih.gov/pubmed/30473539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181290
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