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Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells

Glutamine plays an important role in the metabolism of tumor cells through its contribution to redox homeostasis, bioenergetics, synthesis of macromolecules, and signaling. Triple-negative breast cancers (TNBC) are highly metastatic and associated with poor prognosis. TNBC cells show a marked depend...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Mauro-Lizcano, Marta, López-Rivas, Abelardo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833863/
https://ncbi.nlm.nih.gov/pubmed/29434187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0263-0
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