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Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells

Recent evidences indicate that triple-negative breast cancer (TNBC) cells with a mesenchymal phenotype show a basal activation of the unfolded protein response (UPR) that increases their sensitivity to endoplasmic reticulum (ER) stress although the underlying cell death mechanism remains largely une...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cano-González, Ana, Mauro-Lizcano, Marta, Iglesias-Serret, Daniel, Gil, Joan, López-Rivas, Abelardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833688/
https://ncbi.nlm.nih.gov/pubmed/29374147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0164-7
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