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RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680)
The Aurora kinase family (Aurora A, B and C) are crucial regulators of several mitotic events, including cytokinesis. Increased expression of these kinases is associated with tumorigenesis and several compounds targeting Aurora kinase are under evaluation in clinical trials (a.o. AT9283, AZD1152, Da...
Zapisane w:
| Wydane w: | Cell Death Dis |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833749/ https://ncbi.nlm.nih.gov/pubmed/29434255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0245-7 |
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