Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

Histone deacetylase inhibitors (HDACi) have therapeutic effects in models of various renal diseases including acute kidney injury (AKI); however, the underlying mechanism remains unclear. Here we demonstrate that two widely tested HDACi (suberoylanilide hydroxamic acid (SAHA) and trichostatin A (TSA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Liu, Jing, Livingston, Man J., Dong, Guie, Tang, Chengyuan, Su, Yunchao, Wu, Guangyu, Yin, Xiao-Ming, Dong, Zheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833747/
https://ncbi.nlm.nih.gov/pubmed/29476062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0374-7
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia