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Autophagy in proximal tubules protects against acute kidney injury

Autophagy is induced in renal tubular cells during acute kidney injury, however, whether this is protective or injurious remains controversial. We address this question by pharmacologic and genetic blockade of autophagy using mouse models of cisplatin- and ischemia-reperfusion induced acute kidney i...

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Huvudupphovsmän: Jiang, Man, Wei, Qing-qing, Dong, Guie, Komatsu, Masaaki, Su, Yunchao, Dong, Zheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491167/
https://ncbi.nlm.nih.gov/pubmed/22854643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.261
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