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Autophagy in proximal tubules protects against acute kidney injury

Autophagy is induced in renal tubular cells during acute kidney injury, however, whether this is protective or injurious remains controversial. We address this question by pharmacologic and genetic blockade of autophagy using mouse models of cisplatin- and ischemia-reperfusion induced acute kidney i...

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Hlavní autoři: Jiang, Man, Wei, Qing-qing, Dong, Guie, Komatsu, Masaaki, Su, Yunchao, Dong, Zheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491167/
https://ncbi.nlm.nih.gov/pubmed/22854643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.261
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