Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Treatment of intervertebral disc degeneration (IDD) seeks to prevent senescence and death of nucleus pulposus (NP) cells. Previous studies have shown that sirt6 exerts potent anti-senescent and anti-apoptotic effects in models of age-related degenerative disease. However, it is not known whether sir...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Chen, Jian, Xie, Jun-Jun, Jin, Meng-Yun, Gu, Yun-Tao, Wu, Cong-Cong, Guo, Wei-Jun, Yan, Ying-Zhao, Zhang, Zeng-Jie, Wang, Jian-Le, Zhang, Xiao-Lei, Lin, Yan, Sun, Jia-Li, Zhu, Guang-Hui, Wang, Xiang-Yang, Wu, Yao-Sen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833741/
https://ncbi.nlm.nih.gov/pubmed/29352194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0085-5
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi