Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

Lignende værker

• Evidence for eIF2α phosphorylation-independent effects of GSK2656157, a novel catalytic inhibitor of PERK with clinical implications
  af: Krishnamoorthy, Jothilatha, et al.
  Udgivet: (2014)
• The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress
  af: Rajesh, Kamindla, et al.
  Udgivet: (2016)
• Akt determines cell fate through the negative regulation of the PERK-eIF2α phosphorylation pathway
  af: Mounir, Zineb, et al.
  Udgivet: (2011)
• Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress
  af: Rajesh, K, et al.
  Udgivet: (2015)
• Phosphorylation of eIF2α at Serine 51 Is an Important Determinant of Cell Survival and Adaptation to Glucose Deficiency
  af: Muaddi, Hala, et al.
  Udgivet: (2010)