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MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS

Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease caused by the progressive loss of motor neurons in the brain and spinal cord. It has been suggested that toxicity of mutant SOD1 results from its misfolding, however, it is yet uncle...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Shvil, Neta, Banerjee, Victor, Zoltsman, Guy, Shani, Tom, Kahn, Joy, Abu-Hamad, Salah, Papo, Niv, Engel, Stanislav, Bernhagen, Jurgen, Israelson, Adrian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833700/
https://ncbi.nlm.nih.gov/pubmed/29371591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0130-4
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