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MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS
Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease caused by the progressive loss of motor neurons in the brain and spinal cord. It has been suggested that toxicity of mutant SOD1 results from its misfolding, however, it is yet uncle...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833700/ https://ncbi.nlm.nih.gov/pubmed/29371591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0130-4 |
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