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Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency

Autophagy is a catabolic process to degrade both damaged organelles and aggregated proteins in somatic cells. We have recently identified that autophagy is an executor for mitochondrial homeostasis in embryonic stem cell (ESC), and thus contribute to stemness regulation. However, the regulatory and...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Gong, Jiaqi, Gu, Haifeng, Zhao, Lin, Wang, Liang, Liu, Pinglei, Wang, Fuping, Xu, Haoyu, Zhao, Tongbiao
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833692/
https://ncbi.nlm.nih.gov/pubmed/29348566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0054-z
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