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Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency

Autophagy is a catabolic process to degrade both damaged organelles and aggregated proteins in somatic cells. We have recently identified that autophagy is an executor for mitochondrial homeostasis in embryonic stem cell (ESC), and thus contribute to stemness regulation. However, the regulatory and...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gong, Jiaqi, Gu, Haifeng, Zhao, Lin, Wang, Liang, Liu, Pinglei, Wang, Fuping, Xu, Haoyu, Zhao, Tongbiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833692/
https://ncbi.nlm.nih.gov/pubmed/29348566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0054-z
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