Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization

The liver is the predominant metastatic site for several types of malignancies. Tumor-associated macrophages (TAMs) in the liver play crucial roles in the metastasis process. Shifting tumor-promoting M2-like TAMs toward the M1-like phenotype, which exerts tumor suppressor functions via phagocytosis...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Mengyang, Lai, Xiaofeng, Zhao, Ying, Zhang, Yuan, Li, Minghui, Li, Danxiu, Kong, Jing, Zhang, Yong, Jing, Pengyu, Li, Huichen, Qin, Hongyan, Shen, Liangliang, Yao, Libo, Li, Jipeng, Dou, Kefeng, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833557/
https://ncbi.nlm.nih.gov/pubmed/29445150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0284-8
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