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NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis

BACKGROUND: Paracellular barriers play an important role in the pathogenesis of Inflammatory bowel disease (IBD) and maintain gut homeostasis. N-myc downstream-regulated gene 2 (NDRG2) has been reported to be a tumour suppressor gene and to inhibit colorectal cancer metastasis. However, whether NDRG...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wei, Mengying, Ma, Yongzheng, Shen, Liangliang, Xu, Yuqiao, Liu, Lijun, Bu, Xin, Guo, Zhihao, Qin, Hongyan, Li, Zengshan, Wang, Zhe, Wu, Kaichun, Yao, Libo, Li, Jipeng, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581885/
https://ncbi.nlm.nih.gov/pubmed/33099085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103068
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