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2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation

Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...

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Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833449/
https://ncbi.nlm.nih.gov/pubmed/29352205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0091-7
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