2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation

Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...

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Publicat a:Cell Death Dis
Autors principals: Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833449/
https://ncbi.nlm.nih.gov/pubmed/29352205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0091-7
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