2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation

Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833449/
https://ncbi.nlm.nih.gov/pubmed/29352205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0091-7
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